BENG 221 Mathematical Methods in Bioengineering
Fall 2011
START OF CLASSES
- September 22: Lecture 1
[Slides]
[Notes]
[Laplace tables]
Introduction. Ordinary differential equations
(ODEs), and initial and boundary conditions. Solution of homogeneous and
inhomogeneous ODEs. Eigenvalue and eigenvector analysis, and multimode
analysis. Linear time-invariant systems,
impulse response, and transfer function.
- September 23: Lecture 2, tutorial and problem solving session
[Slides]
[Notes]
[Matlab code]
Introduction to Matlab for linear systems, ODEs and PDEs. Analytical and
numerical techniques. Solution to example problems, using paper and pencil,
and verified by numerical simulation.
WEEK 1
- September 27: Lecture 3
[Notes]
[Matlab code]
Introduction to PDEs. One-dimensional heat equation, and its equivalents in
electrical and chemical transport with applications to biomedical engineering.
Flux through membranes. One-dimensional wave equation in an electrical
transmission line, with open and short circuit termination. Finite difference
PDE approximations.
- September 29: Lecture 4
[Notes]
[Fourier tables]
Solutions to PDEs over bounded and unbounded domains. Separation of
variables. Boundary value problem and solution of the x dependent equation.
Product solution of the PDEs with specified boundary conditions, and Fourier
series expansions of initial conditions. Solutions over infinite domains using
Fourier transforms.
- September 30: Problem solving session--student presentations
WEEK 2
- October 4: Lecture 5
[Notes]
Heat equation. Temperature, thermal energy, and flux. Diffusion of thermal
energy, and boundary conditions on temperature and flux. Thermal equilibrium.
- October 6: Lecture 6
[Notes]
Analytical solution to the inhomogeneous heat equation with space varying
source and boundary conditions. Decomposition of the solution into a
particular steady-state solution, and Fourier series eigenmodes of the
homogeneous solution. Fourier series expansions of initial conditions
revisited.
- October 7: Problem solving session--student presentations
WEEK 3
- October 11: Lecture 7
[Notes]
Analytical solution to inhomogeneous PDEs using Green's functions.
Relationship to impulse response of linear time and space invariant systems.
Green's solution to the inhomogeneous heat equation with time-varying
and space-varying heat source.
- October 13: Lecture 8
[Notes]
[Green's examples]
Extended Green's solution to the inhomogeneous heat equation with time-varying
value and flux boundary conditions. Solutions on infinite domains using
Laplace and Fourier transforms.
- October 14: Problem solving session--student presentations
WEEK 4
- October 18: Lecture 9
[Notes]
Heat and diffusion equation. Time-dependent solutions.
- October 20: Lecture 10
[Notes]
[Sample midterm]
[Solutions]
Review and sample midterm.
- October 21: Problem solving session--student presentations
WEEK 5
- October 25: Midterm
[Midterm]
[Solutions]
[Laplace tables]
- October 27: Lecture 11
[Notes]
Review of vector calculus. Gradients, divergence, curl, and Laplacian.
Transformation between Cartesian, cylindrical, and radial coordinates. Fields
and potentials. Divergence theorem, and Stokes theorem.
- October 28: Problem solving session--student presentations
WEEK 6
- November 1: Lecture 12
[Notes]
Gradient descent optimization. First-order and higher-order methods for
null-finding and function minimization. Introduction to linear and nonlinear
control systems in bioengineering.
- November 3: Lecture 13
[Notes]
[Matlab code]
Numerical solution to PDEs using finite element methods. Orthogonal,
non-orthogonal, and triangular elements. Practical applications in
bioengineering.
- November 4: Problem solving session--student presentations
WEEK 7
- November 8: Lecture 14
[Notes]
Brownian motion, and diffusion. Theory for one-dimensional
displacement. Scaling of diffusion in space and time. Viscous flow, and
Reynolds number.
- November 10: Problem solving session--student presentations
- November 11: Veterans Day
WEEK 8
- November 15: Lecture 15
[Notes]
Electrostatics. Coulomb's law. Electric field and potential. Work and moving
charge. Equivalence of surface/field product and enclosed charge. Gauss's
law, and Poisson's and Laplace's equation. Electric field near and in
conductors. Dielectric phenomena. Capacitance.
- November 17: Lecture 16
[Notes]
[Supplement]
Introduction to electromagnetism using Maxwell's equations. Wave propagation
in homogeneous and inhomogeneous media. Far and near field. RF telemetry and
power delivery. Tissue absorption.
- November 18: Problem solving session--student presentations
WEEK 9
- November 22: Lecture 17
[Notes]
The one dimensional wave equation. The vibrating string as a boundary value
problem. Vibrating string clamped at both ends. Standing waves and summation
of traveling waves.
- November 24: Thanksgiving
WEEK 10
- November 29: Lecture 18
[Notes]
Sound. Transmission of waves in gases. Pressure variation in a sound wave.
- December 1: Lecture 19
[Notes]
[Sample final exam]
[Solutions]
Course review and sample final exam.
- December 2: Problem solving session--student presentations
FINAL EXAM
- December 7: 11:30am-2:29pm, PFBH 161
[Solutions]
-
Richard Haberman, Applied Partial Differential
Equations (4th Edition), Pearson-Prentice Hall, 2004.
-
H. M. Schey, Div, Grad, Curl, and All That: An Informal Text on Vector
Calculus (4th Edition), Norton Press, 2005.
-
Richard Fitzpatrick, Classical
Electromagnetism: An intermediate level course, Univ. Texas, 2006.
-
Albert Einstein, Investigations on the theory of the Brownian movement, Dover
Publications Inc., 1956 (translation from the 1905 original).
-
Wikipedia, the free encyclopedia:
-
Gerard Michon,
Final Answers
on Maxwell's Equations, Numericana, 2009.